UC知道翻译一篇<科学>上的论文
来源：百度知道 编辑：UC知道 时间：2024/09/21 14:46:28
RNA Polymerase IV DirectsSilencing of Endogenous DNA
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition tothe well-known DNA-dependent RNA polymerases I, II, and III. By mutation ofthe two largest subunits (NRPD1a and NRPD2), we show that Pol IV silencescertain transposons and repetitive DNA in a short interfering RNA pathwayinvolving RNA-dependent RNA polymerase 2 and Dicer-like 3. The existenceof this distinct silencing polymerase may explain the paradoxical involvementof an RNA silencing pathway in maintenance of transcriptional silencing.
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition tothe well-known DNA-dependent RNA polymerases I, II, and III. By mutation ofthe two largest subunits (NRPD1a and NRPD2), we show that Pol IV silencescertain transposons and repetitive DNA in a short interfering RNA pathwayinvolving RNA-dependent RNA polymerase 2 and Dicer-like 3. The existenceof this distinct silencing polymerase may explain the paradoxical involvementof an RNA silencing pathway in maintenance of transcriptional silencing.
是关于基因沉默机制（RNA干扰）的文章：粗译如下：
RNA聚合酶IV导致内源DNA的基因沉默
植物还编码除了众所周知的DNA依赖的RNA聚合酶I, II, 和III外，还为RNA聚合酶IV（Pol IV ）编码亚单位。通过使两个大亚单位的突变（NRPD1a和NRPD2），我们展现了Pol IV像包括RNA依赖的RNA聚合酶2和类Dicer3使部分转座子和在一个小(短)的干扰RNA（iRNA）上的重复DNA沉默的途径。这种与基因沉默聚合酶不同的存在，可能解释用来维持转录后基因沉默的RNA失活（不发挥作用）的矛盾问题。